Among films of guys shopping at Victoria's Secret and couples soaking in outside baths, it was a challenge to fit in several double plays and home runs. Sex sells, and assuring better sex truly sells, to the tune of almost $2 billion in annual sales for Viagra alone. Five years after Viagra's acceptance, both Levitra, and Generic Cialis were accepted within months of every other in 2003. To get an erection, it releases nitric oxide into the blood stream, which stimulates cGMP to cause smooth muscle relaxation in the walls of the penile artery, enabling blood into the *****and following erection. 

All 3 of the PDE-5I's are extremely efficient at helping men to achieve erection, irrespective of the primary reason for the original erection dysfunction, with reported reaction rates of 70-80%. Do they work for females? Yes, to some degree. A latest research study registered 200 postmenopausal girls with Sexual arousal disorder in a double blind placebo controlled study. Viagra significantly enhanced sexual sensation in these ladies, with the marked exclusion of those with the primary analysis of Hypoactive sexual desire. 

Thus, it appears that Viagra improves sexual pleasure in women as in guys, but that it does little to reverse a deficiency of libido. In a report of 90 males on SSR Is who documented AASD, half were assigned to variable doses Viagra and half to placebo. 59% of men in the Viagra group reported Much\/very much improved sexual functioning, vs. only 6% of these in the placebo group. Almost all these individuals have been taking 100 mg by the end of the study. Many psychiatrists have observed scientifically that while PDE-5I aid several individuals with AASD accomplish an erection, the extremely common complaint of delayed ejaculation frequently persists. 

Based on circumstantial evidence that high dose PDE-5I appear to assist remedy this problem, scientists at Columbia University performed an open label study of high dose Viagra for continual ejaculatory delay associated with antidepressants. Patients have been told to start with low dose Generic Viagra, and also to keep increasing the dose till they got a response. Of 21 males who began in the trial, four answered to doses from 25 to 100 mg, which is the point where all of us would close up the prescription pad. Following a few individuals dropped out, there were 10 individuals left with continual ejaculatory delay. Nine of them answered to Viagra in the 150-200 mg variety. Patients who tell you that PDE-5Is do not work for them can be utilizing them incorrectly. According to urologists, 40-55% of apparent Viagra non responders are transformed to responders by simple patient education.